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Insect cell-expressed p180erbB3 possesses an impaired tyrosine kinase activity.

Protein kinases share a number of highly conserved or invariant amino acid residues in their catalytic domains, suggesting that these residues are necessary for kinase activity. In p180erbB3, a receptor tyrosine kinase belonging to the epidermal growth factor (EGF) receptor subfamily, three of these...

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Detalles Bibliográficos
Main Authors: Guy, P M, Platko, J V, Cantley, L C, Cerione, R A, Carraway, K L
Formato: Artigo
Idioma:Inglês
Publicado: 1994
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC44559/
https://ncbi.nlm.nih.gov/pubmed/8058768
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