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Mechanisms of Thymoquinone Hepatorenal Protection in Methotrexate-Induced Toxicity in Rats
To investigate mechanisms by which thymoquinone (TQ) can prevent methotrexate- (MTX-) induced hepatorenal toxicity, TQ (10 mg/kg) was administered orally for 10 days. In independent rat groups, MTX hepatorenal toxicity was induced via 20 mg/kg i.p. at the end of day 3 of experiment, with or without...
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| Publicado en: | Mediators Inflamm |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Hindawi Publishing Corporation
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4455533/ https://ncbi.nlm.nih.gov/pubmed/26089605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/859383 |
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