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Protective Mechanisms of Thymoquinone on Methotrexate-induced Intestinal Toxicity in Rats

BACKGROUND: Intestinal toxicity is a serious side effect in methotrexate (MTX) chemotherapy. OBJECTIVE: To investigate the mechanisms by which the anticancer drug MTX-induced intestinal damage could be prevented by thymoquinone (TQ), an active ingredient of Nigella sativa. MATERIALS AND METHODS: TQ...

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Publicado en:Pharmacogn Mag
Main Authors: El-Sheikh, Azza A., Morsy, Mohamed A., Hamouda, Azza H.
Formato: Artigo
Idioma:Inglês
Publicado: Medknow Publications & Media Pvt Ltd 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792005/
https://ncbi.nlm.nih.gov/pubmed/27041864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0973-1296.176106
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