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Killing the hypnozoite – drug discovery approaches to prevent relapse in Plasmodium vivax
The eradication of malaria will only be possible if effective, well-tolerated medicines kill hypnozoites in vivax and ovale malaria, and thus prevent relapses in patients. Despite progress in the 8-aminoquinoline series, with tafenoquine in Phase III showing clear benefits over primaquine, the drug...
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| 發表在: | Pathog Glob Health |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Maney Publishing
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4455353/ https://ncbi.nlm.nih.gov/pubmed/25891812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1179/2047773215Y.0000000013 |
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