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Killing the hypnozoite – drug discovery approaches to prevent relapse in Plasmodium vivax

The eradication of malaria will only be possible if effective, well-tolerated medicines kill hypnozoites in vivax and ovale malaria, and thus prevent relapses in patients. Despite progress in the 8-aminoquinoline series, with tafenoquine in Phase III showing clear benefits over primaquine, the drug...

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Publicado en:Pathog Glob Health
Autores principales: Campo, Brice, Vandal, Omar, Wesche, David L., Burrows, Jeremy N.
Formato: Artigo
Lenguaje:Inglês
Publicado: Maney Publishing 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4455353/
https://ncbi.nlm.nih.gov/pubmed/25891812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1179/2047773215Y.0000000013
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