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Parallel fiber to Purkinje cell synaptic impairment in a mouse model of spinocerebellar ataxia type 27
Genetically inherited mutations in the fibroblast growth factor 14 (FGF14) gene lead to spinocerebellar ataxia type 27 (SCA27), an autosomal dominant disorder characterized by heterogeneous motor and cognitive impairments. Consistently, genetic deletion of Fgf14 in Fgf14(−/−) mice recapitulates sali...
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Publicado no: | Front Cell Neurosci |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Frontiers Media S.A.
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4455242/ https://ncbi.nlm.nih.gov/pubmed/26089778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00205 |
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