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Purkinje Cell Signaling Deficits in Animal Models of Ataxia

Purkinje cell (PC) dysfunction or degeneration is the most frequent finding in animal models with ataxic symptoms. Mutations affecting intrinsic membrane properties can lead to ataxia by altering the firing rate of PCs or their firing pattern. However, the relationship between specific firing altera...

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Detalles Bibliográficos
Publicado en:Front Synaptic Neurosci
Main Authors: Hoxha, Eriola, Balbo, Ilaria, Miniaci, Maria Concetta, Tempia, Filippo
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5937225/
https://ncbi.nlm.nih.gov/pubmed/29760657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsyn.2018.00006
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