The fission yeast MTREC complex targets CUTs and unspliced pre-mRNAs to the nuclear exosome

Cryptic unstable transcripts (CUTs) are rapidly degraded by the nuclear exosome. However, the mechanism by which they are recognized and targeted to the exosome is not fully understood. Here we report that the MTREC complex, which has recently been shown to promote degradation of meiotic mRNAs and r...

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Vydáno v:Nat Commun
Hlavní autoři: Zhou, Yang, Zhu, Jianguo, Schermann, Géza, Ohle, Corina, Bendrin, Katja, Sugioka-Sugiyama, Rie, Sugiyama, Tomoyasu, Fischer, Tamás
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Pub. Group 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4455066/
https://ncbi.nlm.nih.gov/pubmed/25989903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8050
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