The fission yeast MTREC complex targets CUTs and unspliced pre-mRNAs to the nuclear exosome

Cryptic unstable transcripts (CUTs) are rapidly degraded by the nuclear exosome. However, the mechanism by which they are recognized and targeted to the exosome is not fully understood. Here we report that the MTREC complex, which has recently been shown to promote degradation of meiotic mRNAs and r...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Zhou, Yang, Zhu, Jianguo, Schermann, Géza, Ohle, Corina, Bendrin, Katja, Sugioka-Sugiyama, Rie, Sugiyama, Tomoyasu, Fischer, Tamás
Format: Artigo
Language:Inglês
Published: Nature Pub. Group 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4455066/
https://ncbi.nlm.nih.gov/pubmed/25989903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8050
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