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The fission yeast MTREC complex targets CUTs and unspliced pre-mRNAs to the nuclear exosome

Cryptic unstable transcripts (CUTs) are rapidly degraded by the nuclear exosome. However, the mechanism by which they are recognized and targeted to the exosome is not fully understood. Here we report that the MTREC complex, which has recently been shown to promote degradation of meiotic mRNAs and r...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Zhou, Yang, Zhu, Jianguo, Schermann, Géza, Ohle, Corina, Bendrin, Katja, Sugioka-Sugiyama, Rie, Sugiyama, Tomoyasu, Fischer, Tamás
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4455066/
https://ncbi.nlm.nih.gov/pubmed/25989903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8050
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