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MiR-155 modulates the inflammatory phenotype of intestinal myofibroblasts by targeting SOCS1 in ulcerative colitis

Abnormal levels of microRNA (miR)-155, which regulate inflammation and immune responses, have been demonstrated in the colonic mucosa of patients with inflammatory bowel diseases (IBD), although its role in disease pathophysiology is unknown. We investigated the role of miR-155 in the acquisition an...

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Détails bibliographiques
Publié dans:Exp Mol Med
Auteurs principaux: Pathak, Surajit, Grillo, Alessia Rosaria, Scarpa, Melania, Brun, Paola, D'Incà, Renata, Nai, Laura, Banerjee, Antara, Cavallo, Donatella, Barzon, Luisa, Palù, Giorgio, Sturniolo, Giacomo Carlo, Buda, Andrea, Castagliuolo, Ignazio
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454995/
https://ncbi.nlm.nih.gov/pubmed/25998827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2015.21
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