Polarized Cell Motility Induces Hydrogen Peroxide to Inhibit Cofilin via Cysteine Oxidation

Mesenchymal cell motility is driven by polarized actin polymerization [1]. Signals at the leading edge recruit actin polymerization machinery to promote membrane protrusion, while matrix adhesion generates tractive force to propel forward movement. To work effectively, cell motility is regulated by...

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Pubblicato in:Curr Biol
Autori principali: Cameron, Jenifer M., Gabrielsen, Mads, Chim, Ya Hua, Munro, June, McGhee, Ewan J., Sumpton, David, Eaton, Philip, Anderson, Kurt I., Yin, Huabing, Olson, Michael F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454775/
https://ncbi.nlm.nih.gov/pubmed/25981793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2015.04.020
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