Polarized Cell Motility Induces Hydrogen Peroxide to Inhibit Cofilin via Cysteine Oxidation

Mesenchymal cell motility is driven by polarized actin polymerization [1]. Signals at the leading edge recruit actin polymerization machinery to promote membrane protrusion, while matrix adhesion generates tractive force to propel forward movement. To work effectively, cell motility is regulated by...

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Detalhes bibliográficos
Publicado no:Curr Biol
Main Authors: Cameron, Jenifer M., Gabrielsen, Mads, Chim, Ya Hua, Munro, June, McGhee, Ewan J., Sumpton, David, Eaton, Philip, Anderson, Kurt I., Yin, Huabing, Olson, Michael F.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2015
Assuntos:
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454775/
https://ncbi.nlm.nih.gov/pubmed/25981793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2015.04.020
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