Inhibition of proopiomelanocortin expression by an oligodeoxynucleotide complementary to beta-endorphin mRNA.

Gene expression in mammalian cells can be suppressed by oligonucleotides complementary to the target mRNA. This strategy was explored as a means of arresting translation of the prohormone precursor proopiomelanocortin (POMC), used as a model system of peptide messengers that are synthesized and rele...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Spampinato, S, Canossa, M, Carboni, L, Campana, G, Leanza, G, Ferri, S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44547/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8058759/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.17.8072
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