MEK and TGF-beta Inhibition Promotes Reprogramming without the Use of Transcription Factor

The possibility of replacing the originally discovered and widely used DNA reprogramming transcription factors is stimulating enormous effort to identify more effective compounds that would not alter the genetic information. Here, we describe the generation of induced pluripotent stem cells (iPSc) f...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Vrbsky, Jan, Tereh, Tamas, Kyrylenko, Sergiy, Dvorak, Petr, Krejci, Lumir
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454598/
https://ncbi.nlm.nih.gov/pubmed/26039048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127739
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