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MEK and TGF-beta Inhibition Promotes Reprogramming without the Use of Transcription Factor

The possibility of replacing the originally discovered and widely used DNA reprogramming transcription factors is stimulating enormous effort to identify more effective compounds that would not alter the genetic information. Here, we describe the generation of induced pluripotent stem cells (iPSc) f...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Vrbsky, Jan, Tereh, Tamas, Kyrylenko, Sergiy, Dvorak, Petr, Krejci, Lumir
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454598/
https://ncbi.nlm.nih.gov/pubmed/26039048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127739
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