Ethanol-TGFα-MEK Signaling Promotes Growth of Human Hepatocellular Carcinoma

BACKGROUND: Chronic ethanol intake is a significant risk factor for the development of cirrhosis and hepatocellular carcinoma (HCC). The effects of ethanol on extracellular signal-regulated kinase (ERK) activation, transforming growth factor alpha (TGF-α) and HCC growth were examined in this study....

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Main Authors: Hennig, Matthew, Yip-Schneider, Michele T., Klein, Patrick, Wentz, Sabrina, Matos, Jesus M., Doyle, Courtney, Choi, Jennifer, Wu, Huangbing, Norris, Amanda, Menze, Alex, Noble, Stephen, McKillop, Iain H., Schmidt, C. Max
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732720/
https://ncbi.nlm.nih.gov/pubmed/19321179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2008.11.836
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