ALCOHOL INDUCES LIVER NEOPLASIA IN A NOVEL ALCOHOL-PREFERRING RAT MODEL

BACKGROUND: Alcohol is a significant risk factor for development of hepatocellular carcinoma (HCC). To date, no rodent model has demonstrated formation of hepatic neoplasia in the setting of chronic alcohol consumption alone. METHODS: We investigated whether rats selectively bred for high alcohol pr...

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Main Authors: Yip-Schneider, Michele T., Doyle, Courtney J., McKillop, Iain H., Wentz, Sabrina C., Brandon-Warner, Elizabeth, Matos, Jesus M., Sandrasegaran, Kumaresan, Saxena, Romil, Hennig, Matthew E., Wu, Huangbing, Waters, Joshua A., Klein, Patrick J., Froehlich, Janice C., Schmidt, C. Max
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204329/
https://ncbi.nlm.nih.gov/pubmed/21790668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2011.01568.x
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