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Structure and insights into the function of a Ca(2+)-activated Cl(-) channel
Bestrophin calcium-activated chloride channels (CaCCs) regulate the flow of chloride and other monovalent anions across cellular membranes in response to intracellular calcium (Ca(2+)) levels. Mutations in bestrophin-1 (Best1) cause certain eye diseases. Here we present X-ray structures of chicken B...
Enregistré dans:
| Publié dans: | Nature |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4454446/ https://ncbi.nlm.nih.gov/pubmed/25337878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13913 |
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