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Structure and insights into the function of a Ca(2+)-activated Cl(-) channel

Bestrophin calcium-activated chloride channels (CaCCs) regulate the flow of chloride and other monovalent anions across cellular membranes in response to intracellular calcium (Ca(2+)) levels. Mutations in bestrophin-1 (Best1) cause certain eye diseases. Here we present X-ray structures of chicken B...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nature
Päätekijät: Dickson, Veronica Kane, Pedi, Leanne, Long, Stephen B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454446/
https://ncbi.nlm.nih.gov/pubmed/25337878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13913
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