Hepcidin regulation in prostate and its disruption in prostate cancer

Hepcidin is a circulating peptide hormone made by the liver that is a central regulator of systemic iron uptake and recycling. Here we report that prostate epithelial cells also synthesize hepcidin, and that synthesis and secretion of hepcidin are markedly increased in prostate cancer cells and tiss...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Tesfay, Lia, Clausen, Kathryn A., Kim, Jin W., Hegde, Poornima, Wang, Xiaohong, Miller, Lance D., Deng, Zhiyong, Blanchette, Nicole, Arvedson, Tara, Miranti, Cindy K., Babitt, Jodie L., Lin, Herbert Y., Peehl, Donna M., Torti, Frank M., Torti, Suzy V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454355/
https://ncbi.nlm.nih.gov/pubmed/25858146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-2465
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