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Contribution of three dimensional architecture and tumor-associated fibroblasts to hepcidin regulation in breast cancer

Hepcidin is a peptide hormone that negatively regulates iron efflux and plays an important role in controlling the growth of breast tumors. In patients with breast cancer, the combined expression of hepcidin and its membrane target, ferroportin, predict disease outcome. However, mechanisms that cont...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Blanchette-Farra, Nicole, Kita, Daniel, Konstorum, Anna, Tesfay, Lia, Lemler, David, Hegde, Poornima, Claffey, Kevin P., Torti, Frank M., Torti, Suzy V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054540/
https://ncbi.nlm.nih.gov/pubmed/29695834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0243-y
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