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Mir-509-5p joins the Mdm2/p53 feedback loop and regulates cancer cell growth

Although the Mdm2/p53 interaction has been well documented, it is not clear whether there are new microRNAs participating in this regulatory network. Here, we provide evidence that miR-509-5p, which is downregulated in a subset of newly diagnosed cervical cancer and hepatocellular carcinoma tissues...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Ren, Z-J, Nong, X-Y, Lv, Y-R, Sun, H-H, An, P-p, Wang, F, Li, X, Liu, M, Tang, H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454302/
https://ncbi.nlm.nih.gov/pubmed/25144722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.327
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