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Mitochondrial dysfunction induced by a post-translationally modified amyloid linked to a familial mutation in an alternative model of neurodegeneration
Familial British dementia (FBD) is an early-onset non-amyloid-β (Aβ) cerebral amyloidosis that presents with severe cognitive decline and strikingly similar neuropathological features to those present in Alzheimer’s disease (AD). FBD is associated with a T to A single nucleotide transition in the st...
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| Publicado en: | Biochim Biophys Acta |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4454292/ https://ncbi.nlm.nih.gov/pubmed/25261792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2014.09.010 |
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