Mitochondrial dysfunction induced by a post-translationally modified amyloid linked to a familial mutation in an alternative model of neurodegeneration

Familial British dementia (FBD) is an early-onset non-amyloid-β (Aβ) cerebral amyloidosis that presents with severe cognitive decline and strikingly similar neuropathological features to those present in Alzheimer’s disease (AD). FBD is associated with a T to A single nucleotide transition in the st...

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Bibliographic Details
Published in:Biochim Biophys Acta
Main Authors: Todd, Krysti, Fossati, Silvia, Ghiso, Jorge, Rostagno, Agueda
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454292/
https://ncbi.nlm.nih.gov/pubmed/25261792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2014.09.010
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