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Amyloidosis Associated with Cerebral Amyloid Angiopathy: Cell Signaling Pathways Elicited in Cerebral Endothelial Cells

Substantial genetic, biochemical, and in vivo data indicate that progressive accumulation of amyloid-β (Aβ) plays a central role in the pathogenesis of Alzheimer’s disease (AD). Historically centered in the importance of parenchymal plaques, the role of cerebral amyloid angiopathy (CAA)—a frequently...

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Détails bibliographiques
Publié dans:J Alzheimers Dis
Auteurs principaux: Ghiso, Jorge, Fossati, Silvia, Rostagno, Agueda
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467213/
https://ncbi.nlm.nih.gov/pubmed/24670400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-140027
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