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Preamyloid Lesions and Cerebrovascular Deposits in the Mechanism of Dementia: Lessons from Non-β-Amyloid Cerebral Amyloidosis

The importance of amyloid plaques in the pathogenesis of dementia is usually centered on β-amyloid (Aβ) and its role in Alzheimer's disease (AD). However, since fibrillar plaques correlate poorly with neurodegeneration, challenging their importance in the mechanism(s) of dementia, investigators...

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Detalhes bibliográficos
Main Authors: Rostagno, Agueda, Ghiso, Jorge
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826450/
https://ncbi.nlm.nih.gov/pubmed/18322382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000113694
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