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Regulation of caspase-3 processing by cIAP2 controls the switch between pro-inflammatory activation and cell death in microglia

The activation of microglia, resident immune cells of the central nervous system, and inflammation-mediated neurotoxicity are typical features of neurodegenerative diseases, for example, Alzheimer's and Parkinson's diseases. An unexpected role of caspase-3, commonly known to have execution...

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Bibliografski detalji
Izdano u:Cell Death Dis
Glavni autori: Kavanagh, E, Rodhe, J, Burguillos, M A, Venero, J L, Joseph, B
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454160/
https://ncbi.nlm.nih.gov/pubmed/25501826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.514
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