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CD38-mediated Ca(2+) signaling contributes to glucagon-induced hepatic gluconeogenesis

CD38 is a multifunctional enzyme for the synthesis of Ca(2+) second messengers. Glucagon promotes hepatic glucose production through Ca(2+) signaling in the fasting condition. In this study, we investigated the role of CD38 in the glucagon signaling of hepatocytes. Here, we show that glucagon induce...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Rah, So-Young, Kim, Uh-Hyun
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454144/
https://ncbi.nlm.nih.gov/pubmed/26038839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10741
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