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NAADP-mediated Ca(2+) signaling promotes autophagy and protects against LPS-induced liver injury
LPS has been shown to induce hepatocyte autophagy, but little is known about how LPS is able to do this during acute toxic liver injury. Our aim was to determine the existence of any selective Ca(2+) signaling coupling to hepatocyte autophagy in response to LPS. LPS increased the autophagic process...
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| Veröffentlicht in: | FASEB J |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Federation of American Societies for Experimental Biology
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5471520/ https://ncbi.nlm.nih.gov/pubmed/28386045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201601290R |
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