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NAADP-mediated Ca(2+) signaling promotes autophagy and protects against LPS-induced liver injury

LPS has been shown to induce hepatocyte autophagy, but little is known about how LPS is able to do this during acute toxic liver injury. Our aim was to determine the existence of any selective Ca(2+) signaling coupling to hepatocyte autophagy in response to LPS. LPS increased the autophagic process...

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Bibliografiske detaljer
Udgivet i:FASEB J
Main Authors: Rah, So-Young, Lee, Young-Hoon, Kim, Uh-Hyun
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471520/
https://ncbi.nlm.nih.gov/pubmed/28386045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201601290R
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