Subinhibitory Antibiotic Therapy Alters Recurrent Urinary Tract Infection Pathogenesis through Modulation of Bacterial Virulence and Host Immunity

The capacity of subinhibitory levels of antibiotics to modulate bacterial virulence in vitro has recently been brought to light, raising concerns over the appropriateness of low-dose therapies, including antibiotic prophylaxis for recurrent urinary tract infection management. However, the mechanisms...

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Udgivet i:mBio
Main Authors: Goneau, Lee W., Hannan, Thomas J., MacPhee, Roderick A., Schwartz, Drew J., Macklaim, Jean M., Gloor, Gregory B., Razvi, Hassan, Reid, Gregor, Hultgren, Scott J., Burton, Jeremy P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Microbiology 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453531/
https://ncbi.nlm.nih.gov/pubmed/25827417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00356-15
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