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Microbiome Profiling by Illumina Sequencing of Combinatorial Sequence-Tagged PCR Products

We developed a low-cost, high-throughput microbiome profiling method that uses combinatorial sequence tags attached to PCR primers that amplify the rRNA V6 region. Amplified PCR products are sequenced using an Illumina paired-end protocol to generate millions of overlapping reads. Combinatorial sequ...

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Detalhes bibliográficos
Main Authors: Gloor, Gregory B., Hummelen, Ruben, Macklaim, Jean M., Dickson, Russell J., Fernandes, Andrew D., MacPhee, Roderick, Reid, Gregor
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964327/
https://ncbi.nlm.nih.gov/pubmed/21048977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015406
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