Deficiency of the Novel Exopolyphosphatase Rv1026/PPX2 Leads to Metabolic Downshift and Altered Cell Wall Permeability in Mycobacterium tuberculosis

Mycobacterium tuberculosis can persist for decades in the human host. Stringent response pathways involving inorganic polyphosphate [poly(P)], which is synthesized and hydrolyzed by polyphosphate kinase (PPK) and exopolyphosphatase (PPX), respectively, are believed to play a key regulatory role in b...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:mBio
Päätekijät: Chuang, Yu-Min, Bandyopadhyay, Nirmalya, Rifat, Dalin, Rubin, Harvey, Bader, Joel S., Karakousis, Petros C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Microbiology 2015
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453511/
https://ncbi.nlm.nih.gov/pubmed/25784702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02428-14
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