Targeting the insulin-like growth factor receptor and Src signaling network for the treatment of non-small cell lung cancer

BACKGROUND: Therapeutic interventions in the insulin-like growth factor receptor (IGF-1R) pathway were expected to provide clinical benefits; however, IGF-1R tyrosine kinase inhibitors (TKIs) have shown limited antitumor efficacy, and the mechanisms conveying resistance to these agents remain elusiv...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Min, Hye-Young, Yun, Hye Jeong, Lee, Ji-Sun, Lee, Hyo-Jong, Cho, Jaebeom, Jang, Hyun-Ji, Park, Shin-Hyung, Liu, Diane, Oh, Seung-Hyun, Lee, J. Jack, Wistuba, Ignacio I., Lee, Ho-Young
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453276/
https://ncbi.nlm.nih.gov/pubmed/26041671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0392-3
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