Smoking-associated lung cancer prevention by blockade of the beta-adrenergic receptor-mediated insulin-like growth factor receptor activation

Activation of receptor tyrosine kinases (RTKs) is associated with carcinogenesis, but its contribution to smoking-associated lung carcinogenesis is poorly understood. Here we show that a tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced insulin-like growth fact...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Min, Hye-Young, Boo, Hye-Jin, Lee, Ho Jin, Jang, Hyun-Ji, Yun, Hye Jeong, Hwang, Su Jung, Smith, John Kendal, Lee, Hyo-Jong, Lee, Ho-Young
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342599/
https://ncbi.nlm.nih.gov/pubmed/27708216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12342
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