TIF1γ interferes with TGFβ1/SMAD4 signaling to promote poor outcome in operable breast cancer patients

BACKGROUND: The Transforming growth factor β (TGFβ) signaling has a paradoxical role in cancer development and outcome. Besides, the prognostic significance of the TGFβ1, SMAD4 in breast cancer patients is an area of many contradictions. The transcriptional intermediary factor 1γ (TIF1γ) is thought...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Kassem, Loay, Deygas, Mathieu, Fattet, Laurent, Lopez, Jonathan, Goulvent, Thibaut, Lavergne, Emilie, Chabaud, Sylvie, Carrabin, Nicolas, Chopin, Nicolas, Bachelot, Thomas, Gillet, Germain, Treilleux, Isabelle, Rimokh, Ruth
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453047/
https://ncbi.nlm.nih.gov/pubmed/26040677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1471-y
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