Antagonistic regulation of EMT by TIF1γ and Smad4 in mammary epithelial cells

TGF-β is a potent inducer of epithelial-to-mesenchymal transition (EMT), a process involved in tumour invasion. TIF1γ participates in TGF-β signalling. To understand the role of TIF1γ in TGF-β signalling and its requirement for EMT, we analysed the TGF-β1 response of human mammary epithelial cell li...

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Main Authors: Hesling, Cédric, Fattet, Laurent, Teyre, Guillaume, Jury, Delphine, Gonzalo, Philippe, Lopez, Jonathan, Vanbelle, Christophe, Morel, Anne-Pierre, Gillet, Germain, Mikaelian, Ivan, Rimokh, Ruth
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2011
Teme:
Scientific Reports
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128966/
https://ncbi.nlm.nih.gov/pubmed/21597466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.78
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