Src tyrosine kinase inhibits apoptosis through the Erk1/2- dependent degradation of the death accelerator Bik

Src, the canonical member of the non-receptor family of tyrosine kinases, is deregulated in numerous cancers, including colon and breast cancers. In addition to its effects on cell proliferation and motility, Src is often considered as an inhibitor of apoptosis, although this remains controversial....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lopez, J, Hesling, C, Prudent, J, Popgeorgiev, N, Gadet, R, Mikaelian, I, Rimokh, R, Gillet, G, Gonzalo, P
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2012
Pynciau:
Original Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422470/
https://ncbi.nlm.nih.gov/pubmed/22388352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.21
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