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Src tyrosine kinase inhibits apoptosis through the Erk1/2- dependent degradation of the death accelerator Bik
Src, the canonical member of the non-receptor family of tyrosine kinases, is deregulated in numerous cancers, including colon and breast cancers. In addition to its effects on cell proliferation and motility, Src is often considered as an inhibitor of apoptosis, although this remains controversial....
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3422470/ https://ncbi.nlm.nih.gov/pubmed/22388352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.21 |
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