Genomic Context of Azole Resistance Mutations in Aspergillus fumigatus Determined Using Whole-Genome Sequencing

A rapid and global emergence of azole resistance has been observed in the pathogenic fungus Aspergillus fumigatus over the past decade. The dominant resistance mechanism appears to be of environmental origin and involves mutations in the cyp51A gene, which encodes a protein targeted by triazole anti...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Abdolrasouli, Alireza, Rhodes, Johanna, Beale, Mathew A., Hagen, Ferry, Rogers, Thomas R., Chowdhary, Anuradha, Meis, Jacques F., Armstrong-James, Darius, Fisher, Matthew C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453006/
https://ncbi.nlm.nih.gov/pubmed/26037120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00536-15
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