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Itraconazole, Voriconazole, and Posaconazole CLSI MIC Distributions for Wild-Type and Azole-Resistant Aspergillus fumigatus Isolates

Azole resistance in Aspergillus fumigatus is most frequently conferred by mutations in the cyp51A gene encoding 14α-sterol demethylases. TR(34)/L98H and TR(46)/Y121F/T289A are the two most common mutations associated with environmental resistance selection. We studied the minimal inhibitory concentr...

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Bibliographic Details
Published in:J Fungi (Basel)
Main Authors: Buil, Jochem B., Hagen, Ferry, Chowdhary, Anuradha, Verweij, Paul E., Meis, Jacques F.
Format: Artigo
Language:Inglês
Published: MDPI 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162657/
https://ncbi.nlm.nih.gov/pubmed/30158470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jof4030103
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