Therapeutically targetable ALK mutations in leukemia

Genome sequencing is revealing a vast mutational landscape in leukemia, offering new opportunities for treatment with targeted therapy. Here we identify two patients with acute myeloid leukemia and B-cell acute lymphoblastic leukemia whose tumors harbor point mutations in the ALK kinase. The mutatio...

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Publicado en:Cancer Res
Autores principales: Maxson, Julia E., Davare, Monika A., Luty, Samuel B., Eide, Christopher A., Chang, Bill H., Loriaux, Marc M., Tognon, Cristina E., Bottomly, Daniel, Wilmot, Beth, McWeeney, Shannon K., Druker, Brian J., Tyner, Jeffrey W.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453002/
https://ncbi.nlm.nih.gov/pubmed/26032424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-1576
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