Formulation and In Vitro, In Vivo Evaluation of Effervescent Floating Sustained-Release Imatinib Mesylate Tablet

INTRODUCTION: Imatinib mesylate is an antineoplastic agent which has high absorption in the upper part of the gastrointestinal tract (GIT). Conventional imatinib mesylate (Gleevec) tablets produce rapid and relatively high peak blood levels and requires frequent administration to keep the plasma dru...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Kadivar, Ali, Kamalidehghan, Behnam, Javar, Hamid Akbari, Davoudi, Ehsan Taghizadeh, Zaharuddin, Nurul Dhania, Sabeti, Bahareh, Chung, Lip Yong, Noordin, Mohamed Ibrahim
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452730/
https://ncbi.nlm.nih.gov/pubmed/26035710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126874
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