Formulation and In Vitro, In Vivo Evaluation of Effervescent Floating Sustained-Release Imatinib Mesylate Tablet

INTRODUCTION: Imatinib mesylate is an antineoplastic agent which has high absorption in the upper part of the gastrointestinal tract (GIT). Conventional imatinib mesylate (Gleevec) tablets produce rapid and relatively high peak blood levels and requires frequent administration to keep the plasma dru...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kadivar, Ali, Kamalidehghan, Behnam, Javar, Hamid Akbari, Davoudi, Ehsan Taghizadeh, Zaharuddin, Nurul Dhania, Sabeti, Bahareh, Chung, Lip Yong, Noordin, Mohamed Ibrahim
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452730/
https://ncbi.nlm.nih.gov/pubmed/26035710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126874
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