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Association of Organic Cation Transporter 1 with Intolerance to Metformin in Type 2 Diabetes: A GoDARTS Study

Metformin is the most widely prescribed medication for the treatment of type 2 diabetes (T2D). However ~25% of patients treated with metformin develop gastrointestinal (GI) side-effects leading to discontinuation of therapy in approximately 5% cases. We hypothesised that reduced transport of metform...

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Détails bibliographiques
Publié dans:Diabetes
Auteurs principaux: Dujic, Tanja, Zhou, Kaixin, Donnelly, Louise A, Tavendale, Roger, Palmer, Colin NA, Pearson, Ewan R
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452716/
https://ncbi.nlm.nih.gov/pubmed/25510240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-1388
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