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Improving the Quality of Biomarker Discovery Research: the Right Samples and Enough of Them

BACKGROUND: Biomarker discovery research has yielded few biomarkers that validate for clinical use. A contributing factor may be poor study designs. METHODS: The goal in discovery research is to identify a subset of potentially useful markers from a large set of candidates assayed on case and contro...

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Detalhes bibliográficos
Publicado no:Cancer Epidemiol Biomarkers Prev
Main Authors: Pepe, Margaret S., Li, Christopher I, Feng, Ziding
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452419/
https://ncbi.nlm.nih.gov/pubmed/25837819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-14-1227
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