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Biases Introduced by Choosing Controls to Match Risk Factors of Cases in Biomarker Research

BACKGROUND: Selecting controls that match cases on risk factors for the outcome is a pervasive practice in biomarker research studies. Yet, such matching biases estimates of biomarker prediction performance. The magnitudes of bias are unknown. METHODS: We examined the prediction performance of bioma...

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Detalhes bibliográficos
Main Authors: Pepe, Margaret Sullivan, Fan, Jing, Seymour, Christopher W., Li, Christopher, Huang, Ying, Feng, Ziding
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464972/
https://ncbi.nlm.nih.gov/pubmed/22730452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2012.186007
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