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The Ran-GTP Gradient Spatially Regulates XCTK2 in the Spindle

Ran is a small GTP binding protein that was originally identified as a regulator of nucleocytoplasmic transport [1], and subsequently found to be important for spindle formation [2-5]. In mitosis, a gradient of Ran-GTP emanates from chromatin and diminishes toward spindle poles [6]. Ran-GTP promotes...

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Bibliographische Detailangaben
Veröffentlicht in:Curr Biol
Hauptverfasser: Weaver, Lesley N., Ems-McClung, Stephanie C., Chen, Sez-Hon R., Yang, Ge, Shaw, Sidney L., Walczak, Claire E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452415/
https://ncbi.nlm.nih.gov/pubmed/25981788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2015.04.015
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