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Glucocerebrosidase regulates perpetual cell-to-cell transmission of α-synuclein

Deposition of α-synuclein aggregates occurs widely in the central and peripheral nervous systems in Parkinson’s disease (PD). Although recent evidence has suggested that cell-to-cell transmission of α-synuclein aggregates drives the progression of PD, the mechanism by which α-synuclein aggregates sp...

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Enregistré dans:
Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Bae, Eun-Jin, Yang, Na-Young, Song, Miyoung, Lee, Cheol Soon, Lee, Jun Sung, Jung, Byung Chul, Lee, He-Jin, Kim, Seokjoong, Masliah, Eliezer, Sardi, Sergio Pablo, Lee, Seung-Jae
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452288/
https://ncbi.nlm.nih.gov/pubmed/25156829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5755
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