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Structure of the yeast Bre1 RING domain
Monoubiquitination of histone H2B at Lys123 in yeast plays a critical role in regulating transcription, mRNA export, DNA replication, and the DNA damage response. The RING E3 ligase, Bre1, catalyzes monoubiquitination of H2B in concert with the E2 ubiquitin‐conjugating enzyme, Rad6. The crystal stru...
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| Publié dans: | Proteins |
|---|---|
| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley and Sons Inc.
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4452286/ https://ncbi.nlm.nih.gov/pubmed/25864391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24812 |
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