Direct Bre1-Paf1 Complex Interactions and RING Finger-independent Bre1-Rad6 Interactions Mediate Histone H2B Ubiquitylation in Yeast

Recent yeast genetic studies have implicated the ubiquitin-conjugating enzyme and ubiquitin ligase functions of yRad6 and yBre1, respectively, in H2B ubiquitylation. However, there have been no corresponding biochemical analyses demonstrating intrinsic enzyme activities of yRad6 and yBre1 or related...

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Bibliographic Details
Main Authors: Kim, Jaehoon, Roeder, Robert G.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Transcription, Chromatin, and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742823/
https://ncbi.nlm.nih.gov/pubmed/19531475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.017442
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